Damage segregation in fissioning organisms increases population growth rates

نویسندگان

  • Steven N. Evans
  • David Steinsaltz
  • Brian Charlesworth
  • Francois Taddei
چکیده

By analysing microscope images of growing colonies, Eric Stewart and his colleagues at the René Descartes University in Paris, France, proved that direct descendants of old-pole cells grew 2 per cent more slowly, were 3 per cent smaller and were more likely to die (PLoS Biology, vol 3, e 45). Nature, does not seem to do immortality, Stewart says. "Never say never, but in natural organisms it seems unlikely."

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Damage segregation at fissioning may increase growth rates: a superprocess model.

A fissioning organism may purge unrepairable damage by bequeathing it preferentially to one of its daughters. Using the mathematical formalism of superprocesses, we propose a flexible class of analytically tractable models that allow quite general effects of damage on death rates and splitting rates and similarly general damage segregation mechanisms. We show that, in a suitable regime, the eff...

متن کامل

Asymmetric Damage Segregation Constitutes an Emergent Population-Level Stress Response.

Asymmetric damage segregation (ADS) is a mechanism for increasing population fitness through non-random, asymmetric partitioning of damaged macromolecules at cell division. ADS has been reported across multiple organisms, though the measured effects on fitness of individuals are often small. Here, we introduce a cell-lineage-based framework that quantifies the population-wide effects of ADS and...

متن کامل

Asymmetric Segregation of Damaged Cellular Components in Spatially Structured Multicellular Organisms

The asymmetric distribution of damaged cellular components has been observed in species ranging from fission yeast to humans. To study the potential advantages of damage segregation, we have developed a mathematical model describing ageing mammalian tissue, that is, a multicellular system of somatic cells that do not rejuvenate at cell division. To illustrate the applicability of the model, we ...

متن کامل

Growth rate evolution in improved environments under Prodigal Son dynamics

I use an individual-based model to investigate the evolution of cell division rates in asexual populations under chronic environmental enrichment. I show that maintaining increased growth rates over hundreds of generations following environmental improvement can be limited by increases in cellular damage associated with more rapid reproduction. In the absence of further evolution to either incr...

متن کامل

تاثیر نوع منبع نیتروژنی بر برخی خصوصیات فیزیولوژیک دو سویه جلبک آب شور Dunaliella

Abstract As nitrogen source is a necessary element in structure and cell metabolism, studying of nitrogen source and its effect on growth and different behave of photosynthetic organisms has received much attention. In this study, the comparative effects of three nitrogen sources (KNO3, NH4Cl and KNO3+NH4Cl) have been studied on physiological properties of two Dunaliella species, as ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2006